Gene medicine for cancer treatment: Commercially available medicine and accumulated clinical data in China

Loss of p53 function compromises genetic homeostasis, which induces deregulated DNA replication, damages DNA, and subsequently results in increased resistance to anticancer agents. Pharmacological approaches using recombinant adenoviruses (Ad) have been developed to restore the p53 functions. Anothe...

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Main Authors: Ma, Guangyu, Shimada, Hideaki, Hiroshima, Kenzo, Tada, Yuji, Suzuki, Nobuo, Tagawa, Masatoshi
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2009
Teme:
Review
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761194/
https://ncbi.nlm.nih.gov/pubmed/19920899
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