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Chromatin-modifying enzymes as therapeutic targets – Part 1

BACKGROUND: Disease pathogenesis may result from genetic alterations and/or a more diverse group of epigenetic changes. While events such as DNA methylation are well established, there is significant interest in nucleosome remodeling, RNA interference and histone modifications, as mechanisms that un...

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Autors principals: Keppler, Brian R, Archer, Trevor K
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761090/
https://ncbi.nlm.nih.gov/pubmed/18781828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.12.10.1301
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