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Chromatin-modifying enzymes as therapeutic targets – Part 1

BACKGROUND: Disease pathogenesis may result from genetic alterations and/or a more diverse group of epigenetic changes. While events such as DNA methylation are well established, there is significant interest in nucleosome remodeling, RNA interference and histone modifications, as mechanisms that un...

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Detalles Bibliográficos
Main Authors: Keppler, Brian R, Archer, Trevor K
Formato: Artigo
Idioma:Inglês
Publicado: 2008
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761090/
https://ncbi.nlm.nih.gov/pubmed/18781828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.12.10.1301
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