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RUNX2-modifying enzymes: therapeutic targets for bone diseases

RUNX2 is a master transcription factor of osteoblast differentiation. RUNX2 expression in the bone and osteogenic front of a suture is crucial for cranial suture closure and membranous bone morphogenesis. In this manner, the regulation of RUNX2 is precisely controlled by multiple posttranslational m...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Kim, Woo-Jin, Shin, Hye-Lim, Kim, Bong-Soo, Kim, Hyun-Jung, Ryoo, Hyun-Mo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8080656/
https://ncbi.nlm.nih.gov/pubmed/32788656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-020-0471-4
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