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Resistance to rotavirus infection in adult volunteers challenged with a virulent G1P1A[8] virus correlated with serum IgG antibodies to homotypic VP7 and VP4

BACKGROUND: Previously, 18 adult volunteers were orally challenged with the virulent human rotavirus strain D (G1P1A[8],NSP4[B]) (Kapikian, et al., 1983. J. Infect. Dis. 147:95). To identify correlates of resistance to rotavirus infection, we analyzed serum IgA and IgG antibody levels to various rot...

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Detalhes bibliográficos
Main Authors: Yuan, Lijuan, Honma, Shinjiro, Kim, Inyoung, Kapikian, Albert Z., Hoshino, Yasutaka
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760642/
https://ncbi.nlm.nih.gov/pubmed/19785527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/606116
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