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Fibronectin receptor functions in embryonic cells deficient in alpha 5 beta 1 integrin can be replaced by alpha V integrins.

alpha 5 beta 1 integrin mediates cell adhesion to extracellular matrix by interacting with fibronectin (FN). Mouse lines carrying null mutations in genes encoding either the alpha 5 integrin subunit or FN have been generated previously. Both mutations are embryonic lethal with overlapping defects, b...

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書目詳細資料
發表在:Mol Biol Cell
Principais autores: Yang, J T, Hynes, R O
格式: Artigo
語言:Inglês
出版: American Society for Cell Biology 1996
主題:
在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC276022/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8930896/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.7.11.1737
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