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Fibronectin receptor functions in embryonic cells deficient in alpha 5 beta 1 integrin can be replaced by alpha V integrins.

alpha 5 beta 1 integrin mediates cell adhesion to extracellular matrix by interacting with fibronectin (FN). Mouse lines carrying null mutations in genes encoding either the alpha 5 integrin subunit or FN have been generated previously. Both mutations are embryonic lethal with overlapping defects, b...

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Détails bibliographiques
Publié dans:Mol Biol Cell
Auteurs principaux: Yang, J T, Hynes, R O
Format: Artigo
Langue:Inglês
Publié: American Society for Cell Biology 1996
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC276022/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8930896/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.7.11.1737
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