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Sec61p is part of the endoplasmic reticulum-associated degradation machinery

Endoplasmic reticulum-associated degradation (ERAD) is a cellular pathway for the disposal of misfolded secretory proteins. This process comprises recognition of the misfolded proteins followed by their retro-translocation across the ER membrane into the cytosol in which polyubiquitination and prote...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Schäfer, Antje, Wolf, Dieter H
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760108/
https://ncbi.nlm.nih.gov/pubmed/19696741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.231
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