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Sec61p is part of the endoplasmic reticulum-associated degradation machinery
Endoplasmic reticulum-associated degradation (ERAD) is a cellular pathway for the disposal of misfolded secretory proteins. This process comprises recognition of the misfolded proteins followed by their retro-translocation across the ER membrane into the cytosol in which polyubiquitination and prote...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2760108/ https://ncbi.nlm.nih.gov/pubmed/19696741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.231 |
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