Blockade of Wnt-1 signaling leads to anti-tumor effects in hepatocellular carcinoma cells

BACKGROUND: Hepatocellular carcinoma (HCC) is an aggressive cancer, and is the third leading cause of cancer death worldwide. Standard therapy is ineffective partly because HCC is intrinsically resistant to conventional chemotherapy. Its poor prognosis and limited treatment options make it critical...

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Main Authors: Wei, Wei, Chua, Mei-Sze, Grepper, Susan, So, Samuel K
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2009
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759906/
https://ncbi.nlm.nih.gov/pubmed/19778454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-8-76
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