טוען...
Animal Models of Inflammasomopathies Reveal Roles for Innate but not Adaptive Immunity
Cryopyrin (NALP3) mediates formation of the inflammasome, a protein complex responsible for cleavage of pro-IL-1β to its active form. Mutations in the cryopyrin gene, NLRP3, cause the autoinflammatory disease spectrum: cryopyrin-associated periodic syndromes (CAPS). The central role of IL-1β in CAPS...
שמור ב:
Main Authors: | , , , , , , , , , , , , , , |
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פורמט: | Artigo |
שפה: | Inglês |
יצא לאור: |
2009
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נושאים: | |
גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2759865/ https://ncbi.nlm.nih.gov/pubmed/19501000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2009.05.005 |
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