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The GroEL/GroES cis cavity as a passive anti-aggregation device

The GroEL/GroES chaperonin folding chamber is an encapsulated space of ~65 Å diameter with a hydrophilic wall, inside of which many cellular proteins reach the native state. The question of whether the cavity wall actively directs folding reactions or is playing a passive role has been open. We revi...

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Bibliografiske detaljer
Main Authors: Horwich, Arthur L., Apetri, Adrian C., Fenton, Wayne A.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759771/
https://ncbi.nlm.nih.gov/pubmed/19577567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2009.06.049
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