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Sequence and Structure Signatures of Cancer Mutation Hotspots in Protein Kinases
Protein kinases are the most common protein domains implicated in cancer, where somatically acquired mutations are known to be functionally linked to a variety of cancers. Resequencing studies of protein kinase coding regions have emphasized the importance of sequence and structure determinants of c...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2759519/ https://ncbi.nlm.nih.gov/pubmed/19834613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007485 |
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