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Rapid proteomic profiling reveals that human cytomegalovirus UL38 protein antagonizes the tuberous sclerosis protein complex

Although the human cytomegalovirus-coded protein, pUL38, prevents apoptosis, its mode of action has remained unknown. Using an epitope-tagged pUL38 expressed from its normal context in the viral genome, we employed a rapid one-step immunoaffinity purification to isolate interacting proteins, which w...

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Detalhes bibliográficos
Main Authors: Moorman, Nathaniel J., Cristea, Ileana M., Terhune, Scott S., Rout, Michael P., Chait, Brian T., Shenk, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759192/
https://ncbi.nlm.nih.gov/pubmed/18407068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2008.03.002
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