Human Cytomegalovirus pUL83 Stimulates Activity of the Viral Immediate-Early Promoter through Its Interaction with the Cellular IFI16 Protein

The human cytomegalovirus (HCMV) virion protein pUL83 (also termed pp65) inhibits the expression of interferon-inducible cellular genes. In this work we demonstrate that pUL83 is also important for efficient induction of transcription from the viral major immediate-early promoter. Infection with a m...

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Hlavní autoři: Cristea, Ileana M., Moorman, Nathaniel J., Terhune, Scott S., Cuevas, Christian D., O'Keefe, Erin S., Rout, Michael P., Chait, Brian T., Shenk, Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897612/
https://ncbi.nlm.nih.gov/pubmed/20504932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00139-10
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