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Diadenosine Tetraphosphate Reduces Toxicity caused by High-Dose Methamphetamine Administration
Diadenosine tetraphosphate (AP(4)A), two adenosine moieties bridged by four phosphates, is an endogenous purinergic ligand found in brain. Previous studies have shown that AP(4)A reduced neurodegeneration caused by the dopaminergic neurotoxin 6-hydroxydopamine in rat striatum and substantia nigra. T...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2759191/ https://ncbi.nlm.nih.gov/pubmed/19442829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2009.02.003 |
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