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Suppression of endogenous PPARγ increases vulnerability to methamphetamine –induced injury in mouse nigrostriatal dopaminergic pathway

RATIONALE: Methamphetamine is a commonly abused drug and dopaminergic neurotoxin. Repeated administration of high doses of methamphetamine induces programmed cell death, suppression of dopamine release, and reduction in locomotor activity. Previous studies have shown that pretreatment with Peroxisom...

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Detalhes bibliográficos
Principais autores: Yu, Seong-Jin, Airavaara, Mikko, Shen, Hui, Chou, Jenny, Harvey, Brandon K., Wang, Yun
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351577/
https://ncbi.nlm.nih.gov/pubmed/22160138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-011-2595-7
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