Integrin-linked kinase controls vascular wall formation by negatively regulating Rho/ROCK-mediated vascular smooth muscle cell contraction

Vascular smooth muscle cells (VSMCs) form contractile layers around larger blood vessels in a process that is essential for the formation of a fully functional vasculature. Here, we show that integrin-linked kinase (ILK) is required for the formation of a unitary layer of aligned VSMCs around arteri...

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Detalhes bibliográficos
Main Authors: Kogata, Naoko, Tribe, Rachel M., Fässler, Reinhard, Way, Michael, Adams, Ralf H.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758749/
https://ncbi.nlm.nih.gov/pubmed/19797768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.535409
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