Biomarkers Predicting Clinical Outcome of Epidermal Growth Factor Receptor–Targeted Therapy in Metastatic Colorectal Cancer

The monoclonal antibodies panitumumab and cetuximab that target the epidermal growth factor receptor (EGFR) have expanded the range of treatment options for metastatic colorectal cancer. Initial evaluation of these agents as monotherapy in patients with EGFR-expressing chemotherapy-refractory tumors...

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Main Authors: Siena, Salvatore, Sartore-Bianchi, Andrea, Di Nicolantonio, Federica, Balfour, Julia, Bardelli, Alberto
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2009
Teme:
Review
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758310/
https://ncbi.nlm.nih.gov/pubmed/19738166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djp280
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