Targeting the human epidermal growth factor receptor 2 (HER2) oncogene in colorectal cancer

Human epidermal growth factor receptor 2 (HER2) is an oncogenic driver, and a well-established therapeutic target in breast and gastric cancers. Using functional and genomic analyses of patient-derived xenografts, we previously showed that a subset (approximately 5%) of metastatic colorectal cancer...

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Publicat a:Ann Oncol
Autors principals: Siena, S, Sartore-Bianchi, A, Marsoni, S, Hurwitz, H I, McCall, S J, Penault-Llorca, F, Srock, S, Bardelli, A, Trusolino, L
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
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Reviews
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5961091/
https://ncbi.nlm.nih.gov/pubmed/29659677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdy100
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