Intranuclear diffusion and hybridization state of oligonucleotides measured by fluorescence correlation spectroscopy in living cells

Fluorescein-labeled oligodeoxynucleotides (oligos) were introduced into cultured rat myoblasts, and their molecular movements inside the nucleus were studied by fluorescence correlation spectroscopy (FCS) and fluorescence recovery after photobleaching (FRAP). FCS revealed that a large fraction of bo...

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Podrobná bibliografie

Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Politz, Joan C., Browne, Elizabeth S., Wolf, David E., Pederson, Thoru
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1998
Témata:	Biological Sciences
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC27582/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9600914/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.11.6043
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