Properties of Rab5 N-terminal domain dictate prenylation of C-terminal cysteines.

Rab5 is a Ras-related GTP-binding protein that is post-translationally modified by prenylation. We report here that an N-terminal domain contained within the first 22 amino acids of Rab5 is critical for efficient geranylgeranylation of the protein's C-terminal cysteines. This domain is immediately u...

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Publié dans:	Mol Biol Cell
Auteurs principaux:	Sanford, J C, Pan, Y, Wessling-Resnick, M
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Cell Biology 1995
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275815/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7749197/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.6.1.71
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