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Suppression of Constitutive SOS Expression by recA4162 (I298V) and recA4164 (L126V) requires UvrD and RecX in Escherichia coli K-12

Sensing DNA damage and initiation of genetic responses to repair DNA damage are critical to cell survival. In E. coli, RecA polymerizes on ssDNA produced by DNA damage creating a RecA-DNA filament that interacts with the LexA repressor inducing the SOS Response. RecA filament stability is negatively...

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Detalhes bibliográficos
Main Authors: Long, Jarukit Edward, Renzette, Nicholas, Sandler, Steven J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758083/
https://ncbi.nlm.nih.gov/pubmed/19555451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2009.06765.x
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