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UvrD303, a Hyperhelicase Mutant That Antagonizes RecA-Dependent SOS Expression by a Mechanism That Depends on Its C Terminus

Genomic integrity is critical for an organism's survival and ability to reproduce. In Escherichia coli, the UvrD helicase has roles in nucleotide excision repair and methyl-directed mismatch repair and can limit reactions by RecA under certain circumstances. UvrD303 (D403A D404A) is a hyperheli...

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Detalhes bibliográficos
Main Authors: Centore, Richard C., Leeson, Michael C., Sandler, Steven J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648194/
https://ncbi.nlm.nih.gov/pubmed/19074381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01415-08
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