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Androgen Receptor Phosphorylation and Activity Are Regulated by an Association with Protein Phosphatase 1

Androgen receptor (AR) is phosphorylated at multiple sites in response to ligand binding, but the functional consequences and mechanisms regulating AR phosphorylation remain to be established. We observed initially that okadaic acid, an inhibitor of the major PPP family serine/threonine phosphatases...

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Détails bibliographiques
Auteurs principaux: Chen, Shaoyong, Kesler, Cristina T., Paschal, Bryce M., Balk, Steven P.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757959/
https://ncbi.nlm.nih.gov/pubmed/19622840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.043133
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