Caricamento...
Distinct roles for E12 and E47 in B cell specification and the sequential rearrangement of immunoglobulin light chain loci
The E2A gene products, E12 and E47, are critical regulators of B cell development. However, it remains elusive whether E12 and E47 have overlapping and/or distinct functions during B lymphopoiesis. We have generated mice deficient for either E12 or E47 and examined their roles in B cell maturation....
Salvato in:
Autori principali: | , , , , |
---|---|
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
The Rockefeller University Press
2009
|
Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2757879/ https://ncbi.nlm.nih.gov/pubmed/19752184 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20090756 |
Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|