EF hands at the N-lobe of calmodulin are required for both SK channel gating and stable SK–calmodulin interaction

Small conductance calcium-activated potassium (SK) channels respond to intracellular Ca(2+) via constitutively associated calmodulin (CaM). Previous studies have proposed a modular design for the interaction between CaM and SK channels. The C-lobe and the linker of CaM are thought to regulate the co...

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Bibliographic Details
Main Authors: Li, Weiyan, Halling, David B., Hall, Amelia W., Aldrich, Richard W.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757765/
https://ncbi.nlm.nih.gov/pubmed/19752189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200910295
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