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Calcium-dependent stoichiometries of the KCa(2.2) (SK) intracellular domain/calmodulin complex in solution

Ca(2+) activates SK Ca(2+)-activated K(+) channels through the protein Ca(2+) sensor, calmodulin (CaM). To understand how SK channels operate, it is necessary to determine how Ca(2+) regulates CaM binding to its target on SK. Tagless, recombinant SK peptide (SKp), was purified for binding studies wi...

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Detalhes bibliográficos
Main Authors: Halling, D. Brent, Kenrick, Sophia A., Riggs, Austen F., Aldrich, Richard W.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001768/
https://ncbi.nlm.nih.gov/pubmed/24420768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201311007
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