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Inhibition of vascular calcium-gated chloride currents by blockers of K(Ca)1.1, but not by modulators of K(Ca)2.1 or K(Ca)2.3 channels

BACKGROUND AND PURPOSE: Recent pharmacological studies have proposed there is a high degree of similarity between calcium-activated Cl(−) channels (CaCCs) and large conductance, calcium-gated K(+) channels (K(Ca)1.1). The goal of the present study was to ascertain whether blockers of K(Ca)1.1 inhibi...

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Detalhes bibliográficos
Main Authors: Sones, WR, Leblanc, N, Greenwood, IA
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757692/
https://ncbi.nlm.nih.gov/pubmed/19645713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00332.x
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