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The soluble leptin receptor neutralizes leptin-mediated STAT3 signalling and anorexic responses in vivo
BACKGROUND AND PURPOSE: The soluble leptin receptor (SLR) is the major, circulating, leptin-binding protein and, in vitro, the SLR inhibits leptin-binding to cell surface receptors. Here we assessed the effects of the SLR on physiological responses to leptin, in vivo. EXPERIMENTAL APPROACH: SLR and...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2757686/ https://ncbi.nlm.nih.gov/pubmed/19422379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00246.x |
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