Benzyl isothiocyanate-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of MAPK in human pancreatic cancer cells

In our previous studies, we have shown that benzyl isothiocyanate (BITC) inhibits the growth of human pancreatic cancer cells by inducing apoptosis. In the present study, we demonstrate the activation of all the three (MAPK) family members [extracellular signal-regulated protein kinase (ERK), c-jun...

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Huvudupphovsmän: Sahu, Ravi P., Zhang, Ruifen, Batra, Sanjay, Shi, Yan, Srivastava, Sanjay K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2009
Ämnen:
Cancer Prevention
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757546/
https://ncbi.nlm.nih.gov/pubmed/19549704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgp157
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