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Activation of ATM/Chk1 by curcumin causes cell cycle arrest and apoptosis in human pancreatic cancer cells

Curcumin has been shown to inhibit the growth of various types of cancer cells; however, at concentrations much above the clinically achievable levels in humans. The concentration of curcumin achieved in the plasma after oral administration in humans was estimated to be around 1.8 μM. Here, we repor...

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Detalhes bibliográficos
Main Authors: Sahu, R P, Batra, S, Srivastava, S K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694438/
https://ncbi.nlm.nih.gov/pubmed/19401701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605039
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