Deletion of TRPC4 and TRPC6 in mice impairs smooth muscle contraction and intestinal motility in vivo

BACKGROUND & AIMS: Downstream effects of muscarinic receptor stimulation in intestinal smooth muscle include contraction and intestinal transit. We thought to determine whether classical transient receptor potential (TRPC) channels integrate the intracellular signaling cascades evoked by the sti...

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Main Authors: Tsvilovskyy, Volodymyr V., Zholos, Alexander V., Aberle, Thomas, Philipp, Stephan E., Dietrich, Alexander, Zhu, Michael X., Birnbaumer, Lutz, Freichel, Marc, Flockerzi, Veit
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757464/
https://ncbi.nlm.nih.gov/pubmed/19549525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2009.06.046
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