An Isoform-Specific Mutant Reveals a Role of PDP1ε in the Circadian Oscillator

The Drosophila PAR domain protein 1 (Pdp1) gene encodes a transcription factor with multiple functions. One isoform, PDP1ε, was proposed to be an essential activator of the core clock gene, Clock (Clk). However, a central clock function for PDP1ε was recently disputed, and genetic analysis has been...

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Main Authors: Zheng, Xiangzhong, Koh, Kyunghee, Sowcik, Mallory, Smith, Corinne J., Chen, Dechun, Wu, Mark N., Sehgal, Amita
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2009
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757269/
https://ncbi.nlm.nih.gov/pubmed/19726650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2133-09.2009
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