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JETLAG Resets the Drosophila Circadian Clock by Promoting Light-Induced Degradation of TIMELESS

Organisms ranging from bacteria to humans synchronize their internal clocks to daily cycles of light and dark. Photic entrainment of the Drosophila clock is mediated by proteasomal degradation of the clock protein TIMELESS (TIM). We have identified mutations in jetlag—a gene coding for an F-box prot...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Koh, Kyunghee, Zheng, Xiangzhong, Sehgal, Amita
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2767177/
https://ncbi.nlm.nih.gov/pubmed/16794082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1124951
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