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JETLAG Resets the Drosophila Circadian Clock by Promoting Light-Induced Degradation of TIMELESS

Organisms ranging from bacteria to humans synchronize their internal clocks to daily cycles of light and dark. Photic entrainment of the Drosophila clock is mediated by proteasomal degradation of the clock protein TIMELESS (TIM). We have identified mutations in jetlag—a gene coding for an F-box prot...

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Bibliographic Details
Main Authors: Koh, Kyunghee, Zheng, Xiangzhong, Sehgal, Amita
Format: Artigo
Language:Inglês
Published: 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2767177/
https://ncbi.nlm.nih.gov/pubmed/16794082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1124951
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