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Naïve mouse macrophages become activated following recognition of L5178Y lymphoma cells via concurrent ligation of CD40, NKG2D, and CD18 molecules

Under different circumstances, tumors can inhibit or activate macrophage (Mϕ) effector functions. We studied the mechanisms of tumor-Mϕ interactions leading to Mϕ activation. The results show that L5178Y mouse T-cell lymphoma cells can prime naïve mouse Mϕ to subsequent LPS stimulation, resulting in...

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Main Authors: Buhtoiarov, Ilia N., Rakmilevich, Alexander L., Lanier, Lewis L., Ranheim, Erik A., Sondel, Paul M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757113/
https://ncbi.nlm.nih.gov/pubmed/19201847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0800443
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