Tumoristatic effects of anti-CD40 mAb-activated macrophages involve nitric oxide and tumour necrosis factor-α

Effector cells of the innate immune system have diverse functions that can result in tumour inhibition or tumour progression. Activation of macrophages by CD40 ligation has been shown to induce antitumour effects in vitro and in vivo. Here we investigated the role of nitric oxide (NO) and tumour nec...

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Detalhes bibliográficos
Main Authors: Lum, Hillary D, Buhtoiarov, Ilia N, Schmidt, Brian E, Berke, Gideon, Paulnock, Donna M, Sondel, Paul M, Rakhmilevich, Alexander L
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2006
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782283/
https://ncbi.nlm.nih.gov/pubmed/16771862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2006.02366.x
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