Themis controls thymocyte selection through regulation of T cell receptor-mediated signaling

Themis (Thymocyte expressed molecule involved in selection), a member of a family of proteins with unknown functions, is highly conserved among vertebrates. Here we found that Themis is expressed in high amounts in thymocytes between the pre-T cell receptor (TCR) and positive selection checkpoints,...

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Autors principals: Fu, Guo, Vallée, Sébastien, Rybakin, Vasily, McGuire, Marielena V., Ampudia, Jeanette, Brockmeyer, Claudia, Salek, Mogjiborahman, Fallen, Paul R., Hoerter, John A.H., Munshi, Anil, Huang, Yina H., Hu, Jianfang, Fox, Howard S., Sauer, Karsten, Acuto, Oreste, Gascoigne, Nicholas R.J.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757056/
https://ncbi.nlm.nih.gov/pubmed/19597499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1766
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