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Phenotype and Functional Characterization of Long-Term gp100-Specific Memory CD8(+) T Cells in Disease-Free Melanoma Patients Before and After Boosting Immunization

PURPOSE: Effective cancer vaccines must both drive a strong CTL response and sustain long-term memory T cells capable of rapid, recall responses to tumor antigens. We sought to characterize the phenotype and function of gp100 peptide-specific memory CD8(+) T cells in melanoma patients after primary...

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Autori principali: Walker, Edwin B., Haley, Daniel, Petrausch, Ulf, Floyd, Kevin, Miller, William, Sanjuan, Nelson, Alvord, Greg, Fox, Bernard A., Urba, Walter J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756994/
https://ncbi.nlm.nih.gov/pubmed/18698047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-0022
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