gp100 Peptide Vaccine and Interleukin-2 in Patients with Advanced Melanoma

BACKGROUND: Stimulating an immune response against cancer with the use of vaccines remains a challenge. We hypothesized that combining a melanoma vaccine with interleukin-2, an immune activating agent, could improve outcomes. In a previous phase 2 study, patients with metastatic melanoma receiving h...

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Detalhes bibliográficos
Main Authors: Schwartzentruber, Douglas J., Lawson, David H., Richards, Jon M., Conry, Robert M., Miller, Donald M., Treisman, Jonathan, Gailani, Fawaz, Riley, Lee, Conlon, Kevin, Pockaj, Barbara, Kendra, Kari L., White, Richard L., Gonzalez, Rene, Kuzel, Timothy M., Curti, Brendan, Leming, Phillip D., Whitman, Eric D., Balkissoon, Jai, Reintgen, Douglas S., Kaufman, Howard, Marincola, Francesco M., Merino, Maria J., Rosenberg, Steven A., Choyke, Peter, Vena, Don, Hwu, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517182/
https://ncbi.nlm.nih.gov/pubmed/21631324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1012863
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