gp100 Peptide Vaccine and Interleukin-2 in Patients with Advanced Melanoma

BACKGROUND: Stimulating an immune response against cancer with the use of vaccines remains a challenge. We hypothesized that combining a melanoma vaccine with interleukin-2, an immune activating agent, could improve outcomes. In a previous phase 2 study, patients with metastatic melanoma receiving h...

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Autors principals: Schwartzentruber, Douglas J., Lawson, David H., Richards, Jon M., Conry, Robert M., Miller, Donald M., Treisman, Jonathan, Gailani, Fawaz, Riley, Lee, Conlon, Kevin, Pockaj, Barbara, Kendra, Kari L., White, Richard L., Gonzalez, Rene, Kuzel, Timothy M., Curti, Brendan, Leming, Phillip D., Whitman, Eric D., Balkissoon, Jai, Reintgen, Douglas S., Kaufman, Howard, Marincola, Francesco M., Merino, Maria J., Rosenberg, Steven A., Choyke, Peter, Vena, Don, Hwu, Patrick
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517182/
https://ncbi.nlm.nih.gov/pubmed/21631324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1012863
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