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The Adapter Protein SLP-76 Mediates “Outside-In” Integrin Signaling and Function in T Cells
The adapter protein SH2 domain-containing leukocyte protein of 76 kDa (SLP-76) is an essential mediator of signaling from the T-cell antigen receptor (TCR). We report here that SLP-76 also mediates signaling downstream of integrins in T cells and that SLP-76-deficient T cells fail to support adhesio...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2756887/ https://ncbi.nlm.nih.gov/pubmed/19667077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00283-09 |
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