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Generation of a Novel Allelic Series of Cryptochrome Mutants via Mutagenesis Reveals Residues Involved in Protein-Protein Interaction and CRY2-Specific Repression

CRYPTOCHOME proteins are necessary for mammalian circadian rhythms and have many well-established biochemical roles within the molecular clock. While studies examining the effect of null Cry alleles have been informative, they have failed to dissect out the relative importance of, and the molecular...

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Detalhes bibliográficos
Main Authors: McCarthy, Ellena V., Baggs, Julie E., Geskes, Jeanne M., Hogenesch, John B., Green, Carla B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756885/
https://ncbi.nlm.nih.gov/pubmed/19687303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00641-09
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