Role of GTP hydrolysis in microtubule dynamics: information from a slowly hydrolyzable analogue, GMPCPP.
The role of GTP hydrolysis in microtubule dynamics has been reinvestigated using an analogue of GTP, guanylyl-(alpha, beta)-methylene-diphosphonate (GMPCPP). This analogue binds to the tubulin exchangeable nucleotide binding site (E-site) with an affinity four to eightfold lower than GTP and promote...
Αποθηκεύτηκε σε:
| Εκδόθηκε σε: | Mol Biol Cell |
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| Κύριοι συγγραφείς: | , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Cell Biology
1992
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275679/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1421572/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.3.10.1155 |
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