ArPIKfyve homomeric and heteromeric interactions scaffold PIKfyve and Sac3 in a complex to promote PIKfyve activity and functionality

PtdIns(3,5)P(2) is vital in differentiation and development of multicellular organisms because the knockout of the PtdIns(3,5)P(2)-synthesizing enzyme PIKfyve or its associated regulator, ArPIKfyve, is lethal. In previous work with endogenous proteins we identified that Sac3, a phosphatase that turn...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Sbrissa, Diego, Ikonomov, Ognian C., Fenner, Homer, Shisheva, Assia
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756758/
https://ncbi.nlm.nih.gov/pubmed/18950639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.10.009
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky