Genomic Diversity among Drug Sensitive and Multidrug Resistant Isolates of Mycobacterium tuberculosis with Identical DNA Fingerprints

BACKGROUND: Mycobacterium tuberculosis complex (MTBC), the causative agent of tuberculosis (TB), is characterized by low sequence diversity making this bacterium one of the classical examples of a genetically monomorphic pathogen. Because of this limited DNA sequence variation, routine genotyping of...

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Main Authors: Niemann, Stefan, Köser, Claudio U., Gagneux, Sebastien, Plinke, Claudia, Homolka, Susanne, Bignell, Helen, Carter, Richard J., Cheetham, R. Keira, Cox, Anthony, Gormley, Niall A., Kokko-Gonzales, Paula, Murray, Lisa J., Rigatti, Roberto, Smith, Vincent P., Arends, Felix P. M., Cox, Helen S., Smith, Geoff, Archer, John A. C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756628/
https://ncbi.nlm.nih.gov/pubmed/19823582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007407
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