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The control of actin nucleotide exchange by thymosin beta 4 and profilin. A potential regulatory mechanism for actin polymerization in cells.

We present evidence for a new mechanism by which two major actin monomer binding proteins, thymosin beta 4 and profilin, may control the rate and the extent of actin polymerization in cells. Both proteins bind actin monomers transiently with a stoichiometry of 1:1. When bound to actin, thymosin beta...

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Detalhes bibliográficos
Main Authors: Goldschmidt-Clermont, P J, Furman, M I, Wachsstock, D, Safer, D, Nachmias, V T, Pollard, T D
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC275662/
https://ncbi.nlm.nih.gov/pubmed/1330091
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