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The effect of the immunophilin ligands rapamycin and FK506 on proliferation of mast cells and other hematopoietic cell lines.

The immunosuppressive drugs FK506 and cyclosporin A have an identical spectrum of activities with respect to IgE receptor (Fc epsilon RI)-mediated exocytosis from mast cells and T cell receptor-mediated transcription of IL-2. These findings suggest a common step in receptor-mediated signal transduct...

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Bibliografiska uppgifter
Huvudupphovsmän: Hultsch, T, Martin, R, Hohman, R J
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1992
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC275659/
https://ncbi.nlm.nih.gov/pubmed/1384815
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