טוען...

The immunosuppressive and toxic effects of FK-506 are mechanistically related: pharmacology of a novel antagonist of FK-506 and rapamycin

FK-506 inhibits Ca(2+)-dependent transcription of lymphokine genes in T cells, and thereby acts as a powerful immunosuppressant. However, its potential therapeutic applications may be seriously limited by several side effects, including nephrotoxicity and neurotoxicity. At present, it is unclear whe...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
פורמט: Artigo
שפה:Inglês
יצא לאור: The Rockefeller University Press 1992
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2119351/
https://ncbi.nlm.nih.gov/pubmed/1380976
תגים: הוספת תג
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