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The immunophilin-ligands FK506 and V-10,367 mediate neuroprotection by the heat shock response

1. The macrolid FK506 is widely used in transplantation to suppress allograft rejection. FK506 and its derivatives are powerful neuroprotective molecules, but the underlying mechanisms remain to be resolved. We have previously shown that the FK506 mediated neuroprotection against oxygen radicals is...

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Detalhes bibliográficos
Main Authors: Klettner, Alexa, Herdegen, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573741/
https://ncbi.nlm.nih.gov/pubmed/12642403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705132
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