Llwytho...

Biochemical characterization of hyperactive β2-chimaerin mutants revealed an enhanced exposure of C1 and Rac-GAP domains

Recent studies established that the Rac-GAP β2-chimaerin plays important roles in development, neuritogenesis, and cancer progression. A unique feature of β2-chimaerin is that it can be activated by phorbol esters and the lipid second messenger diacylglycerol (DAG), which bind with high affinity to...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sosa, Maria Soledad, Lewin, Nancy E., Choi, Sung-Hee, Blumberg, Peter M., Kazanietz, Marcelo G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756504/
https://ncbi.nlm.nih.gov/pubmed/19618918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9010623
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